Hif-1 alpha protein

WebThis antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, … Web3 de jul. de 2003 · Endothelial PAS domain-containing protein 1. Gene. EPAS1. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 870. Protein existence. Evidence at protein ... Hypoxia-inducible factor 2-alpha (HIF-2-alpha; HIF2-alpha) Member of PAS protein 2; PAS domain-containing protein 2; Gene names. …

Hypoxia Increases ATX Expression by Histone Crotonylation in a HIF …

Web4 de abr. de 2024 · HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain cd19727 Location: 13 → 83 bHLH-PAS_HIF1a_PASD8; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in hypoxia-inducible factor 1-alpha (HIF1a) and similar proteins; XM_006515478.4 → XP_006515541.1 hypoxia-inducible factor 1-alpha isoform X2. … Web11 de abr. de 2024 · The elevations in HIF-1α and HIF-2α protein levels indicated that hypoxia reactions were successfully induced by CoCl 2 and 1% O 2 treatment (Figure … the original heater treater https://h2oattorney.com

HIF1A - Wikipedia, la enciclopedia libre

Web9 de abr. de 2024 · To answer to these questions, we treated epithelial HaCaT and breast cancer MCF-7 cells with different ZnO-NR concentrations. Our results showed that ZnO-NR treatments increased cell death through ROS accumulation, HIF-1α and endothelial PAS domain protein 1 (EPAS1) activation, and induction of autophagy and mitophagy in both … WebHIF-1 alpha, ARNT Interacting Protein, MOP1. eCl@ss: 32160702. NACRES: NA.41. Recommended Products. Slide 1 of 10. 1 of 10. Sigma-Aldrich. H6536. Monoclonal Anti-HIF-1α antibody produced in mouse ~1 mg/mL, clone H1α67, purified immunoglobulin, buffered aqueous solution. View Price and Availability. Web11 de abr. de 2024 · The elevations in HIF-1α and HIF-2α protein levels indicated that hypoxia reactions were successfully induced by CoCl 2 and 1% O 2 treatment (Figure 1C,D). ATX induction was also observed in human colon cancer DLD1 and Hela cells treated with CoCl 2 or cultured under hypoxic conditions (1% O 2 ) ( Figure S1 ). the original hebrew bible in english kjv

HIF-1 alpha detection in WB protocol Abcam

Category:Recombinant Human HIF-1 alpha GST (N-Term) Protein

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Hif-1 alpha protein

Recombinant Human HIF-2 alpha/EPAS1 GST (N-Term) Protein

Web9 de dez. de 2014 · HIF-1 alpha contained in a nuclear extract, binds specifically to the HIF-1 alpha response element. The HIF transcription factor complex is detected by addition of a specific primary antibody directed against HIF-1 alpha. A secondary antibody conjugated to HRP is added to provide a sensitive colorimetric readout at 450 nm. WebKnow comprehensive HIF-1 alpha protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction. U.S.A. …

Hif-1 alpha protein

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WebThis antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry, and gel shift procedures. By Western blot, this antibody detects an ∽116 kDa protein representing HIF-1 alpha after hypoxic induction in COS cells.

WebHIF1-alpha (HIF1A) is a subunit of HIF1, which is a transcription factor found in mammalian cells cultured under reduced oxygen tension. HIF-1 is a heterodimer consisting of an alpha and beta subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors. Web1 mg/mL: Formule: PBS with 0.05% sodium azide: Numéro d’ordre du gène: Q16665, Q61221, O35800: Symboles de gène(s) HIF1A: Immunogène: A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein. Quantité: 100 μL: Primaire ou secondaire: Primary: Espèces cibles: Rat, Rabbit, Non-human Primate, Mouse, Human ...

Web結構. 缺氧大部分需要氧氣呼吸的物種，都擁有保守序列HIF-1。 其轉錄都有嚴格的調控機制。HIF-1是由一個α亞基和一個β亞基組成的異源蛋白二聚體，而β亞基是一種 芳香烃受体核转位子 （ 英语 ： Aryl hydrocarbon receptor nuclear translocator ） （ARNT） 。 HIF-1屬於鹼性螺旋-環-螺旋（bHLH）家族中的PER-ARNT-SIM ... Web3 de ago. de 2024 · Some studies have clarified the role of HIF-1α in the pathogenesis of viral hepatitis, mainly with regard to hepatitis B and C. Hepatitis B virus (HBV) encodes the viral tumor protein transactivator protein X (HBx), which promotes extracellular matrix modification through the HIF/LOX pathway in liver cancer , and HBx mutation affects the …

Web12 de abr. de 2024 · Scientific Reports - MicroRNA-142-3p promotes renal cell carcinoma progression by targeting RhoBTB3 to regulate HIF-1 signaling and GGT/GSH pathways Skip to main content Thank you for visiting ...

WebProduct Specific Information. Description: This Mgc3 monoclonal antibody detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not … the original heat wheat productsWebCommon gene targets for HIF-1 and HIF-2 include VEGFA and GLUT1 (5). The HIF-2 alpha subunit is rapidly targeted and degraded by the ubiquitin proteasome system under normoxic conditions. This process is mediated by oxygen-sensing enzymes, prolyl hydroxylase domain enzymes (PHDs), which catalyze the hydroxylation of key proline … the original hebrew bible pdfWebHIF1A es un factor de transcripción con dominios HLH - PAS encontrado en células de mamíferos que crecen en concentraciones bajas de oxígeno. Juega un papel esencial en la respuesta celular y sistémica a la hipoxia. 5 HIF1A es una de las clases de factores inducibles por hipoxia, una familia que incluye HIF1A, HIF2A y HIF3A . the original helmet sunblockerWebHypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 that is encoded by the HIF1A gene. The Nobel Prize in Physiology or Medicine … the original hellfire clubWeb30 de jan. de 2003 · HIF-1 alpha stability regulation initiates a complex biological response that allows cells to act appropriately to meet patho-physiological situations of decreased … the original hick lifeWeb3 de abr. de 2024 · This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta … the original herd ramsWebProtein target information for Hypoxia-inducible factor 1-alpha (human). Find diseases associated with this biological target and compounds tested against it in bioassay … the original hebrew bible in english pdf